Production methods and Synthetic of resveratrol
Production methods TLC: This method can be used resveratrol and Polygonum cuspidatum other anthraquinones effective separation. TLC conditions: mobile phase: 3 n-hexadecane solution of ammonium bromide (CTAB)-acetyl acetone (8:1.4) in slightly alkaline solution; stationary phase: polyamide ceiling. Take Polygonum cuspidatum powder set conical flask, add 95 amount of ethanol, dipping a few hours, take the point on the polyamide plate ethanol solution to the developing agent to start up, you can isolate resveratrol l8]. Supercritical fluid technology: Cao Yong and other supercritical CO. Fluid technology Polygonum cuspidatum extract from veratryl alcohol to obtain a preliminary extraction conditions _9]. The technology has the ability extraction, extraction rate, low operating temperature, extraction time fast, simple process, easy operation, cleaning, etc., represent the future extraction of resveratrol and even the direction of development of Chinese medicine. Synthetic To 3,5-hydroxyphenyl methanol as starting material, by methylation, bromination, Arbuzov rearrangement reaction of an intermediate 3,5 dimethoxy benzyl phosphate, and then with anisaldehyde by Wittig-Horner condensation and de-methylation of 5-step reaction of resveratrol. Advantages are: less reaction steps, easy to operate, to generate selective high trans-resveratrol _1. It was also the anise alcohol as raw material, bromination, Arbuzov rearrangement reaction intermediates of methoxy benzyl phosphate, and then with 3,5-methoxybenzaldehyde through Wittig-Horner condensation reaction and de-A based synthesis of 4-step reaction product of trans-resveratrol. The synthetic route advantages: fewer reaction steps, easy to get cheap raw materials. |
Contact Us
TEL: +86-21-50321522+86-21-50321520
Fax: +86-21-51069122
Mail: info@chinafooding.com
Web: www.chinafooding.com
Constantly strive towards:
★ High quality products
★ Professional support
★ Total solution for food
★ Reasonable price
★ Credible friendly cooperation
Fooding Next Exhibitions:
Exhibition: IFTech Pakistan 2017
Place: Karachi, Pakistan
Time: 1st-3rd Aug 2017
Booth No.: 5-169